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Stem Cell Therapy for Parkinson's Disease

Managing Parkinson's isn't the only option anymore.

For years, the clinical goal has been to manage symptoms. Mesenchymal stem cell  (MSCs) therapy takes a different approach by working at the source of neuronal loss and neuroinflammation driving the disease forward. This neuroprotective stem cell treatment is available at our clinic in Pereira, Colombia.

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What is Parkinson's disease

A condition defined by what medicine hasn't addressed

Parkinson’s disease is a progressive neurodegenerative condition in which dopamine-producing neurons in the brain gradually break down. As those neurons are lost, the brain loses its ability to coordinate movement — producing tremors, rigidity, and slowed movement that worsen over time.

At its root, the condition involves abnormal protein aggregation in the brain and a breakdown of the blood-brain barrier that normally regulates what enters and exits the central nervous system. When the barrier fails, inflammation follows and neuronal damage accelerates.

Standard treatments from levodopa to deep brain stimulation are designed to manage what’s already happening. They don’t slow neuronal loss, and they don’t address the underlying biology driving it.

Current treatment approaches primarily focus on symptom management. They do not address the prevention of neuronal damage which is why there is a critical clinical need for neuroprotective strategies that offer the potential to replace lost neurons. Regenerative medicine has emerged as a central focus of attention within the medical community precisely because of this gap.

HOW CAN ALEVY'S ADVANCED THERAPY TREATMENTS HELP YOU?

Five ways regenerative therapy targets Parkinson's disease

Advanced therapy does more than manage symptoms. By working at the cellular level, our treatments support your body’s ability to repair, reduce inflammation, and restore function. Here is what that can look like for our patients.

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Protects the blood-brain barrier

MSC-derived secretome protects the blood-brain barrier against alpha-synuclein aggregates reducing the neuroinflammation and neuronal damage that follow when the barrier breaks down. Source: Marzookian et al., Int J Biol Macromol 2025

Reduces disease-driving protein buildup

Exosome therapy has shown the capacity to inhibit alpha-synuclein aggregation or the misfolded protein at the center of Parkinson's pathology targeting the mechanism of progression, not only its effects. Source: Zhuo et al., Stem Cell Res Ther 2023

Neuroprotective and anti-inflammatory

Mesenchymal stem cells modulate both the adaptive and innate immune response in the brain, suppressing the chronic neuroinflammation that drives disease progression and neuronal loss. Source: Tambe et al., Parkinsonism Relat Disord 2024

Addresses premotor symptoms

Sleep disturbances, mood changes, and loss of smell often precede motor symptoms by years. MSC biotherapy has shown improvements in premotor presentations which is a dimension most conventional treatments don't reach. Source: Sun et al., Chin Neurosurg J 2023

Motor function improvements

A systematic review and meta-analysis of stem cell transplantation in Parkinson's patients found significant improvements in motor scores and clinical condition across studies. Source: Zhuo et al., Stem Cell Res Ther 2023 Vij et al., Cytotherapy 2024

The research

What the clinical and scientific evidence shows for Parkinson's Stem Cell Therapy

Safety studies in humans are consistent: stem cell therapy has a very low incidence of adverse effects and is not associated with serious events. Evidence from efficacy studies continues to strengthen with improvements in clinical condition, imaging findings, and neuropsychological scores. Stem cells regenerate damaged areas of the brain and provide neurotrophic support.

Safety and efficacy of adipose-derived MSC therapy in elderly Parkinson's patients

READ STUDY

Efficacy and efficacy-influencing factors of stem cell transplantation in Parkinson's disease: systematic review and meta-analysis

READ STUDY

Phase 1 study of intranasal neural stem cell transplantation in Parkinson's disease

READ STUDY

HOW IT WORKS

5 Steps to Your Advanced Therapy Treatment Plan

01

Schedule Your Consultation

Book a free consultation with one of our Patient Care Specialists who will provide guidance and answer your questions.

02

Send Your Medical Records

Our clinical team reviews your diagnosis, history, and current treatment at no cost, and with no obligation to proceed.

03

Receive Your Personalized Plan

A personalized plan prepared by our physicians based on your specific case. Your referring physician can review it alongside you.

04

Plan Your Visit

Our patient support team will assist you with scheduling your treatment and help coordinate your visit, making the process stress-free.

05

Ongoing Care and Support

After your treatment, we stay connected to monitor your progress and provide continued guidance. Our team is dedicated to your long-term well-being, ensuring you get the best results from your therapy.

Start your personalized plan

ABOUT ALEVY

What separates Alevy from the options available at home

Regulatory restrictions in the US and Canada limit what clinics can offer in cell dosage, sourcing, and protocol design. Alevy operates under international standards that give patients access to what those markets currently can’t provide.

ISO-certified biotechnology laboratory

Our lab in Pereira operates under international quality standards with processes and documentation that most clinics in North America and Europe cannot match in-house.

Wharton's jelly MSC sourcing

Ethically sourced mesenchymal stem cells from umbilical cord tissue that are SCT compliant, high potency, and with a low immune rejection profile. The same cell source linked to blood barrier protection in recent research.

High-dose protocols

Cell dosage ranges that exceed what regulatory restrictions currently permit in the US and Canada and is administered under direct clinical supervision by our medical team.

10+ years of clinical experience

Our medical team has treated complex neurological cases across more than 10 years. Providing experience that most regenerative medicine clinics at this stage of the field don't have.

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FREQUENTLY ASKED QUESTIONS

Your Questions Answered

Human safety data on stem cell therapy in Parkinson's disease is consistent across the literature. Clinical studies and meta-analyses confirm a very low incidence of adverse effects, with no serious events reported in trials to date. Phase 1 studies (including intranasal neural stem cell transplantation and expanded access programs using MSC therapy in elderly PD patients) have demonstrated safety and tolerability across different administration routes. At Alevy, every treatment protocol is reviewed and approved by our medical team before any intervention begins.

Treatment cost depends on your specific protocol — including stem cell dosage, exosomes, number of sessions, individual case complexity and additional treatments that you would like to include in your package. Because no two Parkinson's cases are identical, we don't publish a fixed price. The most accurate way to get pricing is to submit your medical records for review. Our clinical team will assess your case and provide a full treatment protocol with associated costs. There is no commitment required to receive an asessment and quotation.

Our patient's successful outcomes and clinical evidence show that MSCs can help treat Parkinson's disease. A 2024 systematic review and meta-analysis published in Frontiers in Neurology found significant improvements in motor function and clinical condition in Parkinson's patients treated with stem cell therapy. Separate research has confirmed improvements in neuropsychological scores, premotor symptoms, and neuroinflammation markers. Current therapy does not cure Parkinson's disease but evidence supports its role as a neuroprotective, disease-modifying approach that may stop the progression of the disease and goes beyond what symptom management alone can offer.

Stem cell and exosome therapy targets two processes that conventional treatment doesn't reach: the breakdown of the blood-brain barrier and the accumulation of the proteins that drive neuroinflammation and neuronal loss. Rather than compensating for symptoms, MSCs work to protect existing neurons, reduce inflammation, and support repair at the cellular level. How this applies to your specific case is something our medical team can walk you through directly after having reviewed your medical history and a virtual consultation. Request your protocol and we'll schedule a consultation with our physician to answer your questions.

In most cases, yes and we don't ask patients to discontinue their current treatment before or during therapy. Levodopa, dopamine agonists, MAO-B inhibitors, and other standard Parkinson's medications can generally be maintained alongside regenerative treatment. Our medical team reviews your full medication history as part of the protocol design process, and any interactions or adjustments are identified before treatment begins. We work alongside your neurologist, and your existing care team remains part of the process.